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The European Journal of Orthodontics 1988 10(1):52-61; doi:10.1093/ejo/10.1.52
© 1988 by European Orthodontic Society
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Clefts of the lip and/or palate in monozygotic twins

Toni M. Davies1 and Robin P. J. Thompson

University Hospital of South Manchester England

1Miss T M Davies Department of Orthodontics Withington Hospital Nell Lane West Didsbury Manchester England

Twins concordant for cleft lip and/or palate are an uncommon but valuable resource in the study of congenital clefts. Two sets of monozygotic twins concordant for cleft lip and/or palate are described. An interesting feature is that the pairs show variability in the extent of the malformation, but all the children are affected. The genetics of cleft lip and/or palate susceptibility are discussed.


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